Millions of people suffering from Type 2 diabetes could be cured of the disease if they just lost weight, a new study suggests.
Scientists at Newcastle University have shown the disease is caused by fat accumulating in the pancreas and losing less than one gram from the organ can reverse the life-limiting illness and restore insulin production.
Type 2 diabetes affects 3.3 million people in England and Wales and, until now, was thought to be chronic. It can lead to blindness, stroke, kidney failure and limb amputation.“For people with Type 2 diabetes, losing weight allows them to drain excess fat out of the pancreas and allows function to return to normal”Professor Roy Taylor, Newcastle University
But now researchers at Newcastle have shown that the disease can be reversed, even in obese people who have had the condition for a long time.
18 obese people with Type 2 diabetes who were given gastric band surgery and put on a restricted diet for eight weeks were cured of their condition. During the trial the patients, aged between 25 and 65, lost an average of 2.2 stone, which was around 13 per cent of their body weight. Crucially they also lost 0.6 grams of fat from their pancreas, allowing the organ to secrete normal levels of insulin.
The prevalence of diabetes in children shot up dramatically between 2000 and 2009, a new study shows.
The amount of type 1 diabetes, an autoimmune disease, climbed 21% from 2000 to 2009, to 1.93 per 1,000 children. The prevalence of type 2 diabetes — which is associated with obesity — jumped more than 30% in the same period, to a rate of 0.46 per 1,000 kids, according to a study presented Saturday at the Pediatric Academic Societies’ meeting in Vancouver, Canada.
Nationwide, nearly 167,000 children and teens younger than 20 have type 1 diabetes, while more than 20,000 have type 2, says study author Dana Dabelea, of the Colorado School of Public Health in Aurora, Colo.
“These increases are serious,” Dabelea says. “Every new case means a lifetime burden of difficult and costly treatment and higher risk of early, serious complications.”
The new study, published in the Journal of the American Medical Association, is the most comprehensive available, said David Ludwig, director of the New Balance Foundation Obesity Prevention Center at Boston Children’s Hospital, who was not involved in the study. The research, called the SEARCH for Diabetes in Youth Study, included 3 million children and adolescents in different regions of the USA.
Researchers acknowledge that the study doesn’t include information from the last five years.
“We don’t know what happened in the last five years,” Ludwig says. “Most likely, things have gotten worse.”